December 10, 2025
Helicobacter pylori (H. pylori) infection is one of the most common causes of gastric discomfort, ulcers, and long-term gastrointestinal complications worldwide. Nepal, with its diverse population, varying sanitation conditions, and limited diagnostic access in rural areas, experiences a high prevalence of this infection.
Understanding symptoms, risk factors, diagnostic methods, and treatment pathways is essential for both patients and healthcare providers.
What Is H. pylori?
H. pylori is a spiral-shaped bacterium that colonizes the stomach lining. It weakens the mucosal barrier, leading to:
- Gastritis
- Peptic ulcers
- Acid reflux
- Increased risk of stomach cancer
Transmission often occurs through contaminated water, food, or close household contact.
Common Symptoms of H. pylori Infection
- Upper abdominal pain
- Bloating
- Nausea
- Loss of appetite
- Frequent burping
- Burning sensation
- Unexplained weight loss
However, many people show no symptoms, making screening crucial.
Diagnosis of H. pylori in Nepal
Available methods include:
1. Rapid Diagnostic Tests (RDTs)
Detect H. pylori antigens or antibodies in stool or blood. Fast, affordable, and ideal for primary care settings.
2. Urea Breath Test
Highly accurate but available mostly in advanced labs.
3. Endoscopy with biopsy
Gold standard but invasive.
Why RDTs Are Practical in Nepal
- Widely accessible
- No laboratory setup needed
- Results in minutes
- Suitable for rural healthcare posts
Treatment Options
Standard therapy includes:
Triple Therapy:
- Proton pump inhibitor (PPI)
- Clarithromycin
- Amoxicillin or metronidazole
Quadruple Therapy:
Recommended when resistance is suspected.
Patients must complete the full course to ensure eradication.
Preventing H. pylori Infection
- Drink clean water
- Maintain hygiene practices
- Avoid shared eating utensils
- Seek early diagnosis for gastric symptoms
Novala Biotech provides reliable, fast H. pylori rapid test kits ideal for clinics, pharmacies, and labs across Nepal. Contact us to request product samples or distribution support.